Depression, anxiety and burden of care in caregivers of children with β-thalassemia major

β – thalassemia major is a chronic inherited blood disorder requiring lifelong treatment including transfusion, putting tremendous burden on caregivers of the affected children. Aims were to measure care, prevalence and severity depression anxiety, their association with various socio-demographic illness related factors in children major. A cross-sectional study was conducted 100 suffering from coming Paediatrics department S.S.G. Hospital, Vadodara. Study tools used Zarit Burden Interview, General Health Questionnaire-28, Diagnostic Statistical Manual mental disorders (fifth edition) diagnostic criteria for depressive generalised anxiety disorder, Hamilton Depression Anxiety Rating Scales. Forty seven (47%) had moderate severe care. Fifty four (54%) screened positive having psychiatric morbidity out which thirty five (35%) fourteen (14%) disorder. 24 (68.6%) 9 (64.3%) respectively. care significantly associated lower income those transfusions every 2 weeks or less. Thalassemia has its impact not only patients but also health leading high levels depression, them. They should be routinely provide adequate these individuals.